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Pik 3 Curves 14 mg Feb March 2025.docx MISSING GRAPH I COULD NOT DRAG AND DROP out of ignorance A peak value of 66.7 ug/l =100 and 2.4 hrs as t= 0 was assumed as standard for further calculations

It is the most clinically studied of the three, with topical trials showing collagen, fine-line, and skin-density changes, and a large body of in-vitro work on gene expression and wound healing

Notably, melanotan 2 is equally as potent at inducing tanning as afemelanotide, however with added biological effects due to additional binding at melanocortin receptors 3, 4, and 5 [1, 7]

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Timeline based on Highland Longevity patient data and SURMOUNT clinical trial outcomes

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